Faculty and Staff

Fernando Mendive, PhD

Fernando Mendive, PhD



Title
Center Director
Location
Peru
Pronouns
He/Him/His
Education
Postdoctoral Studies in Molecular Biology
Free University of Brussels, Belgium
PhD in Molecular Biology and Genetics
University of Buenos Aires, Argentina
BS in Biochemistry
University of Buenos Aires, Argentina
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Faculty Profile

During the last two decades, Fernando has been exploring Amazonian biodiversity and the associated indigenous knowledge, two precious heritages deeply interlinked in the Amazonian culture. He believes that these two legacies are not only vital for Amazonian people but also for humanity to thrive. During this period, he has been the scientific coordinator of the Takiwasi Center and the principal investigator of the ATOP Project (Ayahuasca Treatment Outcome Project) focused in the medicinal indigenous knowledge and how it may help non-indigenous people to heal from addictions and other mental diseases that are poorly addressed by the modern paradigm of health. He has also led a phytopharmaceutical laboratory specialized in developing, producing and commercializing natural health products from Amazonian medicinal and aromatic plants. In this role, he conceived and implemented an intercultural methodology that facilitates the dialog and cooperation between indigenous people´s traditional knowledge, pharmaceutical technology, marketing and modern commercial approaches to develop and introduce products into the market, building up impact business models. To achieve this venture, he has collaborated with governmental and non-governmental national and international conservation agencies, indigenous communities and organizations, academic and research institutions to create, fund and execute impact projects.

Before his Amazonian experience, he has been interested in understanding living organisms at the molecular level, from bacteria to humans. For his PhD he studied the function of the human thyroid gland focused on the genetic and molecular mechanisms for the production of thyroid hormones in normal and pathological conditions at University of Buenos Aires and University of Salamanca in Spain. After his dissertation he was invited as guest researcher to Antarctica for a project studying the genetics of bacteria adapted to metabolize hydrocarbons from oil spills at low temperatures with bioremediation purposes. He then moved to Europe for a postdoc position at the Free University of Brussels, School of Medicine where he investigated orphan cellular receptors with unknown functions but conserved along the animal kingdom from flies to humans.


Academics & Research

Research Interests

• Understand the key variables behind the success of conservation projects that promote Eco-Business leaded by indigenous people and small farmers
• Explore the indigenous wisdom and medicine through an intercultural epistemology and how they might contribute to broaden the modern health paradigm

outputs

Publications

Ancient medicine for a modern disease: traditional Amazonian medicine to treat substance use disorders. (2023)

Mendive F, Giovannetti C, García Arce S Am J Drug Alcohol Abuse. 2023 Nov 10:1-14. doi: 10.1080/00952990.2023.2264466. Epub ahead of print. PMID: 37948338.

Ayahuasca Treatment Outcome Project (ATOP): One Year Results from Takiwasi Center and Implications for Psychedelic Science. (2023)

Rush B, Marcus O, García S, Loizaga-Velder A, Spitalier A, Mendive F. J Stud Alcohol Drugs. 2023 Aug 24. doi: 10.15288/jsad.23-00005. Epub ahead of print. PMID: 37615330.

Ginger: An Introduced Foreign Species and Its Recognition as a Traditional Medicine Plant by the Peruvian Awajun Populations. (2022)

Renatto Canepa, Mayra Sihuay, Elsa Wajai, and Fernando Mendive in Socio-Ecological Systems and Decoloniality-Convergence of Indigenous and Western Knowledge edited by Deepa Pullanikkatil and Kerry Hughes, Springer Nature, 2022, page. 299-324.

Cholinergic Agonists against Covid-19 in Humans. Results from a Randomized Open Label Pilot Trial. (2022)

Jose-Gabriel Leon, Fabio Restrepo, Mario León, Mateo Politi, Fernando Mendive and Orlando Angulo. EC Pharmacology and Toxicology 10.7 (2022): 09-24. DOI: 10.31080/ecpt.2022.10.00757

Editorial: Beyond the Pharmacology of Psychoactive Plant Medicines and Drugs: Pros and Cons of the Role of Rituals and Set and Setting. (2021)

Alex K. Gearin, Luis E. Luna, Fernando Mendive, Marco Leonti, Claudio Ferrante, Luigi Menghini and Matteo Politi. Front. Pharmacol. 2021. Front. Pharmacol. 12:804254. doi: 10.3389/fphar.2021.804254

Implementation of Nagoya Protocol on access and benefit-sharing in Peru: Implications for researchers. (2020)

Friso F, Mendive F, Soffiato M, Bombardelli V, Hesketh A, Heinrich M, Menghini L and Politi M. Journal of Ethnopharmacology, 2020, Sept, 259, 112885. doi.org/10.1016/j.jep.2020.112885

Traditional knowledge as a business model: Takiwasi and Ampik Sacha (Peru). Lena Katzmarski, Flavia Noejovich, Manuel Rojas, Luis Rosa-Perez y Fernando Mendive in “20 years of Biotrade. Connecting People, the planet and Markets”. (2017)

United Nations Conference on Trade and Development. United Nations Publication, 2017, page. 22-23.

Grants and Awards

2002. Postdoctoral Grant. Institute of Interdisciplinary Research in Molecular and Human Biology (IRIBHM), Faculty of Medicine, Universite Libre de Bruxelles. Awarded by: Franqui Foundation. Duration: 2 years

1998. Research Grant for Foreign Studies “Splicing Regulation of the Human Thyroglobulin Gene”; Molecular Medicine Laboratory. Faculty of Medicine, University of Salamanca, Spain. Awarded by: Spanish Agency for International Cooperation (AECI). Duration: 8 months.

1996: Graduate Research Grant. “Structural Organization and Regulation of the Human Thyroglobulin Gene”. University of Buenos Aires. Duration: 2 years

1998. Research Grant for Foreign Studies “Splicing Regulation of the Human Thyroglobulin Gene”; Molecular Medicine Laboratory. Faculty of Medicine, University of Salamanca, Spain. Awarded by: Spanish Agency for International Cooperation (AECI). Duration: 8 months. 1996: Graduate Research Grant. “Structural Organization and Regulation of the Human Thyroglobulin Gene”. University of Buenos Aires. Duration: 2 years

1993: Undergraduate Research Grant. “Structural Organization and Regulation of the Human Thyroglobulin Gene”. Chair of Genetics and Molecular Biology, Faculty of Pharmacy and Biochemistry, UBA. Awarded by: University of Buenos Aires. Duration: 2 years

Presentations

“Building bridges between Traditional Medicine and Modern Medicine”. "I Simposio Nacional: Jardines botánicos y su importancia para la salud y alimentación en el siglo XXI. Investigando y Conservando la Biodiversidad Vegetal y Cultural del País”

Centro Nacional de Salud Intercultural, Instituto Nacional de Salud, Ministerio de Salud del Perú. Del 31 de agosto al 02 de septiembre de 2021

“Environmental care and sustainable use of natural resources in Peru within the framework of the development of the phytopharmaceuticals industry”

Para el Ciclo de Reuniones Técnicas titulado Aprovechamiento Sostenible de las Plantas Medicinales”. Centro Nacional de Salud Intercultural, Instituto Nacional de Salud, Ministerio de Salud del Perú. 18 de agosto de 2021.

"The Medicinal Forest Products as an instrument for the conservation and development of the Amazon: dream or reality?"

Semana Forestal 2020. Centro Federado de Ciencias Forestales, Facultad de Ciencias Forestales, Universidad Nacional Agraria La Molina. 30 noviembre al 02 diciembre 2020. Panelist at the II Exchange Forum Peru – Honduras.

“Forest Management and Climate ChangeEuroclima Program +097: progress, lessons learned and challenges”

PUR Projet, Fundación Helvetas Honduras, Fundación Madera Verde y Fundación Amazonía Viva. Del 2 al 13 de noviembre 2020

“Experience of the Takiwasi Laboratory promoting a Biotrade Business Model with Indigenous Peoples in the San Martín Region”

1ra Feria Virtual de Emprendimientos de Indígenas y Productos del Bosque en San Martín. Paz y Esperanza. 13 de noviembre de 2020.

“On reductionism and complexity: Lessons that medicinal plants and Amazonian Traditional Medicine give us"

Webinar Internacional “Retos en las investigaciones de plantas medicinales en la Amazonía peruana”. Instituto de Investigación de la Amazonía Peruana. 14 de agosto de 2020.

“Successful experiences of business initiatives that implement the BioTrade model”

Cadenas priorizadas de sacha inchik y plantas medicinales. Programa Virtual de Fortalecimiento en Biocomercio para las regiones San Martín, Cusco, Junín, Huancavelica y Loreto. Ministerio de Comercio Exterior y Turismo. 28 de septiembre a 02 octubre 2020.

“Value Chains of Medicinal Plants”. Forum: “Intercambio de Experiencias en el Manejo Forestal y Fauna Silvestre en la Región San Martín”

Moyobamba, San Martín, Perú. 24 de julio de 2019. Use of Non-Timber Forest Resources”. III Encuentro Amazónico de Conservación Voluntaria y Comunal “Amazonia que Late”. Moyobamba, San Martín, Perú. 7 y 8 de diciembre de 2017.